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Liquid Filling and Stoppering Machine

Liquid Filling and Stoppering Machine

The liquid filling and stoppering machine is primarily used for glucose, antibiotics and other infusion liquids, which can complete filling and stoppering operations under room temperature and high temperature conditions. The equipment is also suitable for amino acids, fat emulsion, oral liquid, nutrition liquid and biological agents.

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Performance Characteristics
  • The liquid filling and stoppering machine adopts Germany GEMU pneumatic diaphragm valves for filling, ensuring high accuracy. In addition, it achieves No Bottle, No Filling, resulting in no waste of liquid.
  • During filling process, there is no forced friction of mechanical parts, which prevents particulate pollution. This conforms to GMP requirements.
  • The filling heads can be easily, quickly assembled and disassembled. In fact, users just need to loosen two M6 bolts for disassembly purpose. Additionally, the bottle inlet screw features mobile structure, so it can be easily replaced with screw of different specification by only removing and installing two M8 × 25 bolts. This allows convenient change of infusion bottles in different sizes.
  • The sensitive level gauge in the filling barrel is located at a distance from the liquid inlet, so the inlet tube will have no effect on it when filling liquid. In addition, the liquid filling and stoppering machines stably rotate at low speed, which contributes to the smooth liquid level, thus ensuring the stability of the pressure in the filling barrel.
  • The machine is easy to operate. All settings can be set directly from human-machine interface. The electronic control system adopts advanced PLC and variable frequency speed control technologies, which ensures smooth, convenient startup, shutdown and specification change operations.
  • With CIP (clean-in-place) and SIP (sterilization-in-place) unit, the machine can be thoroughly cleaned and sterilized to meet high hygienic standards.
  • The liquid products are immediately conveyed to the stoppering device after filling procedure, so possible pollution caused by long distance delivery is avoided.
  • The machine adopts vacuum stoppering and mechanical positioning. Only after the rubber stoppers are in the accurate place, the stoppering operation can be performed. So, the qualification rate is high.
Main Technical Parameters
Model GCS6/6 GFS10/10 GCS16 GFS24/10 GFS36/20 GFS48/20
Applied bottle size 50 ml, 100 ml, 250 ml, 500ml
Capacity 30-60 bottle/min 40-100 bottle/min 60-150 bottle/min 120-250 bottle/min 200-350 bottle/min 350-500 bottle/min
Filling heads 6 10 16 24 36 48
Stoppering heads 6 10 10 10 20 20
Metering error ±1.5 % (standard container)
Electric capacity 4.0 kW 4.0 kW 4.0 kW 4.0 kW 4.0 kW 4.0 kW
Compressed air consumption 0.5 m³/h (0.6MPa) 0.8 m³/h (0.6MPa) 1.5 m³/h (0.6MPa) 2.0 m³/h (0.6MPa) 3.2 m³/h (0.6MPa) 4.5 m³/h (0.6MPa)
Outer dimension (mm) 1250X1050X2350 1300X1100X2350 1600X1250X2350 1750X1530X2350 2330X1900X2350 2580X2300X2350
Note: In the above table, the capacity is inversely proportional to the bottle size. Hence, the bigger the bottle size, the lower the capacity. The specific details are correct based on the tender documents.

We are a liquid filling and stoppering machine manufacturer based in China. We offer an extensive line of products, including all in one bottle washing and filling machine, light checking machine, co-extrusion non-PVC IV bag film production line, and more.
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Standardized & Customized Pharmaceutical Processing Equipment

We ensure strict quality control for pharmaceutical machinery, complying with ISO9001:2008 and adhering to cGMP, European GMP, US FDA GMP, and WHO GMP standards.
Our equipment is designed to meet diverse production needs, including non-PVC soft bag, PP bottle, and glass bottle IV production lines, as well as automatic ampoule and vial washing, filling, and sealing systems. We also offer solutions for oral liquid processing, dialysis fluid filling, and pre-filled syringe filling and sealing.

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